Not really, we already know that Saul isn't dying because the show is centered around him; the protagonist of a show isnt dying on the 1st or 2nd episode. Being a prequel has nothing to do with this predictability
I'm not talking about the 1st or 2nd episode. We know he's not going to die period. There isn't going to be a situation in which Saul will die in the last episode like Walt. Due to that, we know, he's never going to be in any REAL danger. What's most likely gonna go down is that people around him will be put in danger and since he's a lawyer and all he's going to have to get them out of it.