I don't understand why Dwight says he doesn't like playing in pick and rolls (because he clearly isn't a dominant post player without having 4 other 3 point specialists spacing the court)... I always thought that it was going to be Nash/Amare Lite with him (he can't shoot jumpers, but he also is tougher to get around for defenders). It seemed like there would be enough spacing for it to work (even with Pau out there, although he isn't the ideal stretch 4 obviously), and it even seemed to work a few times when Nash came back from the injury (I'm thinking specifically against the Warriors at the end of the game).
The reality is NOT that he isn't quick enough to do it (at least from what I've seen in the past, he could be quick enough I think... the effects of his injury still have something to do with that now, but I don't think it would be a problem). It is that he DOES NOT want to.
So, since he doesn't want to do that, the Lakers have some sort of hybrid offense... attempted fast pace with post up players. Nash has had to deal with this before, in a way... when the Suns got Shaq (for about half of the season, under D'Antoni... the Suns fell from close to 1st in the west to the 8th seed by the end of the year, and then got beat 4-1 by the Spurs in the first round).
As bad as the Suns were with the Shaq/D'Antoni combination, they went 18-11 after the Shaq trade (starting with the first game he played, which was, of course, against the Lakers). The fact that they were better than the Lakers are right now blows my mind, because I see some similarities (granted, it's obviously not a perfect comparison).