FlyerThanDelta: I assume your meaning is to start both Sproles and Trent as your two RBs. Richardson's been practicing and good to go. Philly's run defense is improved but Trent still should get yards. Wouldn't be completely surprised if he touched 100 on the ground. If that's the case, Decker, Young, and Ced in that order for your Flex.
I'd start D-Jax, Garcon, Demaryius, Blackmon in that order.
No way for Randy. He should never start over Torrey Smith. Ry Williams is an interesting one because Beanie is questionable. I'd still start Trent regardless but it's closer if Beanie sits and Ry starts.
I'm low on Demaryius this week but I probably wouldn't start a backup in Michael Bush over him, even against the Colts.
Proshares: Donald Brown. See him getting a large number of touches on the ground and through the air on swing passes, check-downs, etc.
Definitely Torrey. I might take a shot on MJD because Ingram is fairly limited in a PPR. So Ingram for the safe, conventional play. MJD for risk, potential high reward.
Fred Jackson, easily. Ced is not getting yards against GB. I'd be shocked if he posts over 50 on the ground.