Your right on one of your points. The heart transplant, which is THE MOST serious of all organ transplants, has so many things that can go wrong during surgery, during recovery in the hospital and long after one is discharged from the hospital. Patients can't even be in the sun for very long and should use hats and even use an umbrella to keep the sun off. So many things to harm a patient.
The immunosuppressants that would be prescribed are pretty rock solid now. They're totally safe. It's if you miss a dose, that can be costly at the beginning. Once they get the patient on the proper regiment and dose, and monitor blood work for many weeks to see how the body is reacting to said medication, then it becomes a routine engraved in your mind to take every day. I got a nice large pill organizer I use twice a day. Nice thing is that pretty much all anti rejection medication is all generic now, so based on insurance, it's relatively cheap $10-30 depending on dose and if it's 30 or 90 days).
When I got my transplant back in 2003, NOTHING was generic except Prednisone, lol. And I took 16 pills in the morning and 6 at night back in the beginning (I take 11 & 5 now). And let me tell you, those meds were pricey even with good insurance back then. But eventually the patents ran out and allowed generics for basically all meds which is such a good thing. He really has no concept of reality and what he's really dealing with.
After having mine, I am doing EVERYTHING I need to do to not need another one as going in the first time I didn't know what to expect post surgery. Now, remembering all the pain I was in, all the lines I had hooked up to me, the blood bypass machine in my major arteries, and some 90 staples for the scar (which I dig) yeah, I don't want to go thought that crap again!