- Jan 16, 2011
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In world first, South Africa's Afrigen makes mRNA COVID vaccine using Moderna data
South Africa's Afrigen Biologics has used the publicly available sequence of Moderna Inc's mRNA COVID-19 vaccine to make its own version of the shot, which could be tested in humans before the end of this year, Afrigen's top executive said on Thursday.
www.reuters.com
CAPE TOWN, Feb 3 (Reuters) - South Africa's Afrigen Biologics has used the publicly available sequence of Moderna Inc's (MRNA.O) mRNA COVID-19 vaccine to make its own version of the shot, which could be tested in humans before the end of this year, Afrigen's top executive said on Thursday.
The vaccine candidate would be the first to be made based on a widely used vaccine without the assistance and approval of the developer. It is also the first mRNA vaccine designed, developed and produced at lab scale on the African continent.
The World Health Organization (WHO) last year picked a consortium including Afrigen for a pilot project to give poor and middle-income countries the know-how to make COVID vaccines, after market leaders of the mRNA COVID vaccine, Pfizer (PFE.N), BioNTech (22UAy.DE) and Moderna (MRNA.O), declined a WHO request to share their technology and expertise.
Biovac, a partly state-owned South African vaccine producer, will be the first recipient of the technology from the hub. Afrigen has also agreed to help train companies in Argentina and Brazil.
Terblanche said Afrigen was also working on a next generation mRNA vaccine that didn't need freezing temperatures for storage, required for the Pfizer and Moderna doses, and which would be better suited to Africa, which is often dealing with high temperatures and poor health facilities and infrastructure.
"We will only make our clinical trial batch probably in six months from now, (meaning) ... fit for humans. And the target is November 2022," Terblanche added.